Despite the prevalence of empirical practice, evidence supporting the use of transcranial magnetic stimulation (TMS) in treating Bipolar Depression (BD) is sparse compared to that for unipolar Depression.
Therefore, this study aimed to conduct a retrospective observational analysis using TMS registry data to compare the efficacy of TMS treatment for BD and unipolar Depression.
However, a highly relevant article that discusses Deep TMS for Bipolar Disorder (BD) is https://www.sciencedirect.com/science/article/pii/S240584402403319X.
Bipolar Disorder, sometimes referred to as manic-depressive illness, is a complex brain condition.
This condition affects a substantial portion of the adult population, with millions of individuals experiencing it each year.
For instance, about 2.6 percent of American adults aged 18 and older are estimated to have bipolar disorder in any given year.
Similar to chronic illnesses such as diabetes or heart disease, Bipolar Disorder requires ongoing management throughout a person's life.
Given its association with the brain's reward system, innovative treatments targeting prefrontal regions and related neural networks, such as Deep Transcranial Magnetic Stimulation (Deep TMS™), are continuously being explored for their potential effectiveness in managing this chronic condition.
A previous clinical trial reported by BrainsWay indicated that their treatment was well-tolerated by all subjects, with a clinical response achieved in 70% of subjects (of whom a vast majority displayed significant improvement) compared with previous antidepressant treatments given to those subjects.
Specifically concerning remission, some studies focusing on TMS for Bipolar Depression have shown promising results.
An analysis of participants undergoing 25 or more TMS sessions for Bipolar Depression found that 41% achieved remission, defined as little-to-no depressive symptoms.
Another study involving a rapid-acting TMS protocol reported 40% remission rates immediately after a short course of treatment, which further grew to 60% one month post-treatment.
The risk of triggering manic episodes with TMS is considered low, comparable to that of some antidepressant medications..
In summary, when compared to traditional treatment modalities for bipolar disorder, deep TMS offers a unique advantage.
It is non-invasive, does not require medication, and has minimal side effects, making it an attractive option for individuals who have not responded well to other treatments or prefer alternative approaches.
References
Neurodivergent Insights. DSM 5 Bipolar 2 Disorder Criteria.
Psychology Today. How Common Is Recovery From Bipolar Disorder?